Influence of the medications containing phospholipids on the serum immunoglobulin g level in calves during formation of colostral immunity
Вантажиться...
Дата
2020
Назва журналу
Номер ISSN
Назва тому
Видавець
НУБіП України
Анотація
The results of the application of the medication “Membranostabil” and
native phospholipid bilayer liposomes based on soybean lecithin developed by this
research group for correction of serum immunoglobulin G (IgG) content in newborn
calves during colostral immunity formation are presented. The indices of IgG content in
blood serum of newborn calves have been investigated in dynamics - from the birth till
the age of 11 days. Studies were performed on newborn calves of three groups (control,
and two experimental ones) of the Ukrainian black-and-white dairy breed. The level
of IgG was investigated by electrophoresis in polyacrylamide gel Quantitative estima-
tion of protein fractions was performed by scanning the electrophoregram, with their
subsequent graphical reconstruction and calculation by relative units or area using a
computer program. It is established that “Membranostabil” medication and native
liposomes from phospholipid bilayer based on soybean lecithin activate transport of
immunoglobulins in small intestine and promote a significant increase of content of
serum IgG compared to calves of the control group. The content of IgG in the serum of
newborns calves of both experimental groups at 6 hours of age significantly increased
and remained higher throughout the duration of the experiment, except for the calves
of the first experimental group at the age of 7 days, compared with calves in the control
group. The dynamics with comparative analysis of serum IgG content between calves
of individual groups is shown. The increase of content of serum IgG in newborn calves
is one of factors preventing early immunodeficiency, sepsis, development of digestive
disorders, and other diseases of young animals.
Опис
Ключові слова
colostral immunity, colostrum, immunoglobulin G (IgG), newborn calves, membranostabil
Бібліографічний опис
Influence of the medications containing phospholipids on the serum immunoglobulin g level in calves during formation of colostral immunity / S.I. Golopura, M.I. Tsvilikhovsky, B.V. Popadiuk // Український часопис ветеринарних наук. – К. : НУБіП України, 2020. - Том 11, № 1. – С. 6 - 14